Maternal nutrition during pregnancy influences the neurodevelopment of the fetus, as is strikingly apparent in the case of folate deficiencies and increased risk for neural tube defects. Given the crucial role that many micronutrients play in the development and functioning of the central nervous system, it is plausible that maternal nutrition during pregnancy may also influence offspring risk of developing autism spectrum disorders (ASD). Numerous studies have now been conducted examining a variety of aspects of maternal nutrition in pregnancy and risk of ASD. The aim of this panel is to present key findings from four cohorts representing a diversity of epidemiological study designs, source populations, and geographic regions. Data will be presented regarding offspring risk of ASD in relation to pre-conceptual and prenatal micronutrient supplementation, maternal BMI, weight gain during pregnancy, prenatal vitamin D exposure, and prenatal polyunsaturated fatty acid exposure.