Objectives: To conduct a prospective comparison of diagnostic conclusions using DSM-IV and DSM-5 criteria within a clinic setting.
Methods: All participants were seen for diagnostic evaluation at the University of North Carolina TEACCH Autism Program across multiple centers in North Carolina. Assessments included administration of the Autism Diagnostic Observation Schedule-2 (ADOS-2), the Childhood Autism Rating Scale-2 (CARS-2), and a developmental history interview. Diagnostic conclusions were made on the basis of the direct assessment and observation, developmental history, DSM-IV-TR criteria and on the basis of clinical judgment. In addition, clinicians rated participants on DSM-5 criteria for ASD on the day of the diagnostic. Data collection is ongoing with an anticipated sample size of 150 participants by February 2013. Preliminary evidence was obtained for 14 participants. The participants are representative of a variety of socioeconomic and racial backgrounds from both rural and urban centers throughout the state. The TEACCH Center conducts diagnostic evaluation on all ages from toddlers through adults. The age range of the first 14 participants was 1.09 to 17.06 years (mean= 6.53 years; SD= 4.85).
Results: In preliminary data, 78.6% of the participants assessed received a diagnosis of ASD. All met criteria on both the proposed DSM-5 and DSM-IV criteria.
Conclusions: Preliminary findings show consistency across DSM-IV and DSM-5 diagnosis using a prospective sample suggesting that DSM-5 is not likely to result in fewer diagnoses.
See more of: Clinical Phenotype
See more of: Symptoms, Diagnosis & Phenotype