Objectives: The aim of this study was to conduct a randomized controlled trial of oxytocin nasal spray to treat social impairments found in youth diagnosed with autism. We aimed to determine whether oxytocin nasal spray would improve social interaction, social cognition, and reduce repetitive behavior, in comparison to a placebo nasal spray.
Methods: This trial recruited 50 male participants aged between 12 and 18 who were diagnosed with autism. We assigned each of these individuals to receive either oxytocin (18 or 24 IU) or an identically matched placebo, twice per day over an eight week period in a double blind, between-subjects design.
Results: The complete results of the trial will be presented at this conference. As this trial is yet to be accepted for publication, we do not report results within this abstract. We will discuss results, moderating factors, and limitations of the current study at the time of presentation.
Conclusions: The results provide data on 50 patients with autism recruited into an oxytocin nasal spray treatment trial. This trial demonstrates whether oxytocin nasal spray improves social cognition and behavior in autism. It provides valuable data on the potential of a new treatment for autism spectrum disorders.
See more of: Treatment Trials: Behavioral Interventions
See more of: Prevalence, Risk factors & Intervention