Contribution of the Social Cognition Evaluation Battery “Clacos”

Poster Presentation
Thursday, May 10, 2018: 11:30 AM-1:30 PM
Hall Grote Zaal (de Doelen ICC Rotterdam)
E. Houy-Durand1, S. Morel-Kohlmeyer2, A. Thillay3, M. Barbier4, I. Amado5, L. Brenugat-Herne5, I. Carteau-Martin6, C. Danset-Alexandre5, B. Gaudelus7, J. Graux2, E. Peyroux8, Z. Prost8 and F. Bonnet-Brilhault9, (1)UMR930 Inserm, Université François-Rabelais de Tours, Tours, France, (2)UMR Inserm U930 Imagerie et Cerveau, Université François-Rabelais de Tours, CHRU de Tours, TOURS, France, (3)UMR INSERM U930, Tours Cedex 9, France, (4)UMR Inserm U930 Imagerie et Cerveau, Université François-Rabelais de Tours, TOURS, France, (5)SHU Centre Hospitalier Sainte Anne, PARIS, France, (6)groupe de travail « Cognition » - Institut de Psychiatrie - GDR 3557, TOURS, France, (7)Centre référent de réhabilitation psychosociale et remédiation cognitive CL3R-SUR, Le Vinatier Hospital, Lyon, France, (8)Le Vinatier Hospital, LYON, France, (9)UMR 1253, iBrain, Université de Tours, Inserm, Tours, France
Background: Autism Spectrum Disorders (ASD) is a range of neurodevelopmental disorders characterized by impairments in social communication and interaction and limited interests and repetitive behaviour according to DSM-5 (American Psychiatric Association, 2013). Although social communication impairments are probably shared across several psychiatric disorders including autism, schizophrenia, anxiety disorders and ADHD, they are not well characterized, due to a lack of standardized evaluation tools, especially in adult populations. Our multicentric research group in psychiatry GDR3557 developed since 2011 a new battery for social cognition evaluation named “ClaCoS”, in order to discriminate specific profiles of social cognition disorders that could be common or specific, respectively to autism and schizophrenia (Pinkham et al., 2008). Thus, clinical evaluation of social cognition impairments is still controversial and remains poorly documented. Moreover, we considered social cognition as a multidimensional process (Pinkham et al., 2014), and examined different components some of which are known to be impaired in ASD.

Objectives: Our aim is to assess the sensibility of the ‘ClaCoS’ battery in the evaluation of social cognition impairments in autism. This battery examines multiple domains of social cognition, namely: subjective perception of social impairments, empathy, emotional facial expression recognition, theory of mind, attribution style (i.e. the interpretation of other people’s behaviour), social perception and knowledge of social rules.

Methods: We compared the social cognition abilities of 18 autism spectrum disorders adult patients without intellectual disability and 18 neurotypically developed peers using ClaCoS.

Results: The ASD group showed deficits in facial expression recognition, empathy, theory of mind adjustment as well as social perception and convention knowledge. Furthermore, ASD adults reported subjective complains regarding their social abilities. We also showed correlations between these different components of social cognition, which suggest the relevance of our battery and its interest to discriminate possible ASD sub-group phenotypes.

Conclusions: A larger sample would be of great value to discriminate specific profiles that could be common to autism and schizophrenia. Shared social cognition profiles could help us to apply social cognitive remediation programs more adjusted to a “transnosographic” impairment following a clinical neurodevelopmental approach.