Paradigm Shifts in Approaches to the Early Detection and Treatment of Autism

Over the past few decades, scientists have discovered how early brain development differs in infants and young children with autism, which has helped explain both the challenges and the strengths and abilities that are associated with autism. Furthermore, research has demonstrated the potential of early behavioral intervention to positively influence the trajectory of both behavioral and brain development in children with autism. As our understanding of the biological basis of autism increases, new treatments designed to enhance neuroplasticity and improve outcomes are currently being developed and tested. Clinical trials evaluating these new treatments are incorporating brain-based measures and quantitative, digital assessments of behavioral outcomes. Such digital approaches to behavioral assessment are transforming how we detect and understand autism and improving our ability to assess the efficacy of novel treatments.