The cerebellum has been implicated in the pathogenesis of autism, but the contributions remain poorly understood. Using a combination of sensorimotor tasks, advanced neuroimaging in both preclinical models and humans, and functional circuit neuromodulation in pre-clinical models and humans, speakers within this session have identified key cerebellar regulated circuit mechanisms that offer potential biomarker targets and are demonstrating the potential for circuit neuromodulation of cerebellar regulated circuits as a potential novel therapeutic target for autism behaviors.