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Is Acttrust a New Device to Measure Sleep Problems in Autism?

Poster Presentation
Friday, May 11, 2018: 10:00 AM-1:30 PM
Hall Grote Zaal (de Doelen ICC Rotterdam)
P. Ballester-Navarro1, E. Martínez-Saíto2, E. Fernández Jover3, A. Palazón4 and A. Peiró5, (1)Hospital General Universitario de Aucante, Alicante, Spain, (2)Department of Clinical Pharmacology, Organic Chemistry and Pediatrics, in the University Miguel Hernández, Madrid, Spain, (3)Bioengineer Institute, Elche, Spain, (4)Paediatrics Service, Alicante, Spain, (5)Clinical Pharmacology, Alicante, Spain
Background: Sleep problems in adults on the autism spectrum are poorly studied in adulthood, where insomnia is the most prevalent. Establishing quantitative criteria with an adequate equipment to analyse, is important for translational research.

Objectives: The aim of the study is to compare ActTrust, Condor instruments device with Ambulatory Circadian Monitoring (ACM) a method already validated.

Methods: Adults diagnosed with autism by DSM-5, wore two devices (ActTrust and ACM, 1 week) to study sleep parameters (Sleep onset latency (SOL), Time in bed (TIB), total sleep time (TST), num. of awakenings, wakes after sleep onset (WASO) and sleep efficiency (SE)). Insomnia was defined by any of those conditions SOL>30min, TST<7-9h, WASO>30m, SE<85%. Fisher exact test was used to compare the results. Also, receiver operator characteristic (ROC) curves were generated for all sleep variables to examine sensitivity and specicity of the sleep measures.

Results: Fifty-two adults on the spectrum (age 31 (11) years old, 77% males) completed the study. No significant differences were found for insomnia cases, when compared by Fischer exact test (p =.091). ROC curves for the ACM were greater than for ActTrust (except for TIB and TST), which could mean a better control-case discrimination .

Conclusions: Insomnia prevalence was well estimated by any of the two devices. ROC curves in ACM estimate better insomnia except for TIB and TST. Further studies should be performed to complete ActTrust validation to define SP in autism.

See more of: Technology Demonstration
See more of: Technology Demonstration